James has secured billions from individuals and corporations that harmed New Yorkers' health care access, including over $3 billion from opioid manufacturers for the opioid epidemic and more than $70 million from neglectful nursing homes.

Letitia James is working to reduce gun violence through gun buyback events and enforcement, removing over 9,600 guns from New York streets. Her office has also seized drugs and guns from organized crime rings and pursued justice for hate-based violence, including the 2022 Buffalo Tops Supermarket shooting.

James championed the FAIR Business Practices Act to crack down on predatory lenders, abusive debt collectors, and dishonest mortgage providers. She has also strengthened homeowner protections against deed theft and taken on large companies to protect consumer data and privacy.

James has led efforts to protect children's mental health online and to shield seniors from scams. She has also investigated nursing homes for patient neglect and endangerment before, during, and after the COVID-19 pandemic.

James is leading efforts to protect the 2026 elections from federal attempts to federalize voting. She has urged Congress to reject the SAVE Act and opposed the President's executive order that would have seized state election administration roles.

James has a track record of protecting housing rights, suing landlords who violate renters' rights and those using vouchers for affordable housing. She has won millions for wronged tenants across New York.

James has fought to protect immigrants from the Trump administration's immigration activities, including establishing a Legal Observation Project to monitor federal immigration activity and filing lawsuits to defend birthright citizenship.

James fights for fair wages, good-paying jobs, and organized labor. She works to keep costs down for New Yorkers, including challenging online platforms that raise prices, and has won millions in settlements for workers denied wages and benefits.